Histiocytosis presenting as swelling of orbit and eyelid.

This paper describes the clinical investigation, and light and electron microscope findings in a Pakistani girl who developed bilateral orbital and eyelid swellings in association with lymphadenopathy. The findings do not correlate with any of the previously recognized causes of these symptoms although similarities with some of the lymphoreticular disorders, in particular Hand-Schuller-Christian disease and the recently described sinus histiocytosis with massive lymphadenopathy (Rosai and Dorfman, I969) are present. The nature of the condition and its differential diagnosis and treatment are discussed.